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WDFY1 (基因名), WD repeat and FYVE domain-containing protein 1 (蛋白名), wdfy1_bovin.
产品名称:

Bovine WDFY1/ WD repeat and FYVE domain-containing protein 1 Recombinant Protein

货号:

R8019b

商标:
EIAab®
监管等级:
别名:

WD40- and FYVE domain-containing protein 1

序列号:
Q2KIY3
来源:
E.coli
种属:
Bovine
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Bovine WDFY1 Protein
规格 & 价格: cart
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Bovine WDFY1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Binds PtdIns3P in vitro with high specificity over other phosphoinositides. Interacts (via WD repeat 2) with tyrosine-phosphorylated TLR3 (via TIR domain) in response to poly(I:C). Interacts with TLR4 in response to LPS. Interacts with TICAM1 in response to poly(I:C).


功能:
Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines.


亚细胞位置:
Early endosome


该产品尚未在任何出版物中被引用。
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