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ZFP64 protein activates the MLL gene to encode the MLL fusion protein

from EIAab

About 5% of cases of acute leukemia are diagnosed as mixed leukemia MLL, which is common in infants. The cause is a gene called MLL, which produces a protein of the same name to promote new cell growth. In most cases, MLL is properly regulated by the body and does not cause disease. Unfortunately, in some cases, MLL in...

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10 / 18

2019

A special endonuclease can be used as a cancer treatment target

from EIAab

Branched or lobed DNAs with single-stranded ends are formed during DNA replication and DNA repair in healthy individuals. These single-stranded flap DNAs can be excised by an enzyme such as FEN1 to repair the integrity of the double-stranded state of the DNA.Higher levels of FEN1 have been observed in cancer cells with...

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10 / 17

2019

The effect of amyloid beta shear on AD

from EIAab

The consciousness of the brain is the basis of all human activities, if the brain activity disorder or stop, human life will be seriously threatened. Alzheimer's disease AD is a relatively common brain disease characterized by progressive memory loss and cognitive impairment. It is not yet clear what brain activity...

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10 / 16

2019

Exposure of key genes in the circadian rhythm of the intestinal immune system

from EIAab

The human digestive tract follows a pattern of digesting food and nutrients while awake and replenishing senescent cells while asleep. But shift work and jet lag can disrupt the body clock, which has been linked to increased risks of intestinal infections, obesity, inflammatory bowel disease and colorectal cancer.Now, ...

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10 / 15

2019

New pathways of bacterial carbohydrate metabolism

from EIAab

The study of intestinal microorganisms is one of the most promising fields in the medical field. For example, Dr. Jeffrey i. Gordon's team has reported a link between human gut bacteria and obesity. Scientists have discovered that individual microbes in the human gut have the ability to break down carbohydrates in ...

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10 / 10

2019

Key proteins that link genetics to environmental influences

from EIAab

Researchers at Harvard medical school have identified a protein called epigenetic regulator that is mutated in many autoimmune diseases: SP140, which is also essential for macrophage function and intestinal homeostasis. Many immune-mediated diseases are driven by a combination of genetic predisposition and environmenta...

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10 / 08

2019

Research reveals the brain roots of Parkinson's disease

from EIAab

Researchers at Washington university school of medicine in St. Louis identified the earliest signs of Parkinson's disease in the brain before patients developed Parkinson-related symptoms. The findings, published in the journal Cell, suggest a new view of the disease and could lead to the development of screening t...

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09 / 19

2019

Human - virus protein interactions

from EIAab

A virus is a much smaller infectious organism than a bacterium. To survive, it must find a suitable host to live inside and use protein-protein interaction PPI to dominate the host cell's survival function and absorb nutrients. In turn, host cells use PPI to activate innate antiviral defenses and adaptive immune sy...

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09 / 18

2019

YAP1 is a potential target for the treatment of lung cancer

from EIAab

Cancer stem cells are a group of special cells in a tumor that initiate and maintain the development of cancer through self-renewal and differentiation. These cells are equivalent to the seeds of cancer, which not only support the growth of tumors, but also promote tumor metastasis and recurrence.YAP1 protein can promo...

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09 / 12

2019

Studies show it's never too late to start exercising

from EIAab

A new study from the University of Texas shows that older adults who have never participated in a sustained exercise program have the same ability to build muscle mass as athletes of the same age who train over time.Studies show that even people who don't exercise at all can benefit from resistance training such as...

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09 / 11

2019

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