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Olfactory receptor OR2AT4 regulates your hair growth

from EIAab

The sense of smell is actually a force that has been neglected in the human senses. Researchers from the University of Manchester have discovered a synthetic compound that mimics the smell of sandalwood, which can promote human scalp tissue in the laboratory to maintain hair growth. The principle is that this chemical ...

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01 / 19

2021

An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer’s disease

from EIAab

Neuroinflammation has been increasingly recognized to play a critical role in Alzheimer’s disease AD. The epoxy fatty acids EpFAs are derivatives of the arachidonic acid metabolism pathway and have anti-inflammatory activities. However, their efficacy is limited because of their rapid hydrolysis by the soluble epoxide ...

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12 / 17

2020

Reversal of biological clock restores vision in old mice

from EIAab

With the continuous advancement of science and technology, the quality of life and longevity of human beings have been greatly improved and extended. However, human beings have not yet completely cracked the code of aging, and researchers have been looking for ways to prevent the aging process.On 2 December in the late...

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12 / 04

2020

Asprosin — new hormone involved in hepatic glucose release

from EIAab

Asprosin is a recently discovered fasting-induced hormone that promotes hepatic glucose production. Here we demonstrate that asprosin in the circulation crosses the blood–brain barrier and directly activates orexigenic AgRP+ neurons via a cAMP-dependent pathway. This signaling results in inhibition of downstream anorex...

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11 / 26

2020

Why does the older people have the faster healing for the wound?

from EIAab

Wounds in the elderly heal faster than young people, and there are fewer scars, because there is a compound called stromal cell-derived-factor-1 SDF-1 in the blood of the elderly, University of Pennsylvania School of Medicine Leung and colleagues demonstrated that blocking this substance can affect skin scar formation ...

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11 / 25

2020

Many surfaces carry coronavirus RNA — but not much of it

from EIAab

Swabbing of bank machines, shop-door handles and other frequently touched surfaces in a US city revealed that 8% of samples were positive for SARS-CoV-2 genetic material, but that material was present in small amounts.Amy Pickering at Tufts University in Medford, Massachusetts, and her colleagues repeatedly sampled 33 ...

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11 / 05

2020

COVID deaths linked to air pollution

from EIAab

A study has concluded that long-term exposure to air pollution could be linked to 15% of global deaths from COVID-19. Researchers combined health and disease figures with data about global exposure to particulate matter in the air. “If both long-term exposure to air pollution and infection with the COVID-19 virus come ...

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10 / 29

2020

How do the sleeping cancer cells wake up?

from EIAab

Scientists at the Cold Spring Harbor Laboratory have found a way to reactivate cancer. This new knowledge has inspired a new range of treatments aimed at preventing cancer recurrence and metastasis.Their study found that persistent lung inflammation including lung inflammation caused by exposure to secondhand smoke can...

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10 / 27

2020

Modifying macrophages at the periphery has the capacity to change microglial reactivity and to extend ALS survival

from EIAab

Microglia and peripheral macrophages have both been implicated in amyotrophic lateral sclerosis ALS, although their respective roles have yet to be determined. We now show that macrophages along peripheral motor neuron axons in mouse models and patients with ALS react to neurodegeneration. In ALS mice,...

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10 / 22

2020

SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies

from EIAab

The COVID-19 pandemic presents an urgent health crisis. Human neutralizing antibodies hNAbs that target the host ACE2 receptor-binding domain RBD of the SARS-CoV-2 spike show therapeutic promise and are being evaluated clincally. To determine structural correlates of SARS-CoV-2 neutralization, we solved 8 new structure...

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10 / 15

2020

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