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Deletion of the Ago2 gene prevents obesity and diabetes in mice

from EIAab

Obesity and obesity-related diseases, such as type 2 diabetes and liver disease, constitute a major burden on global health. Researchers from the Cincinnati Children's Hospital Medical Center reported that blocking RNA silencing in the liver of mice allowed animals to Stay away from obesity and diabetes.The team th...

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11 / 14

2019

Anti-aging molecule contained in blood vessels - β-hydroxybutyric acid

from EIAab

A study led by Georgia State University showed beta-hydroxybutyrate produced during fasting or calorie restriction. It has an anti-aging effect on the vascular system, which can reduce and alleviate blood vessel-related diseases such as cardiovascular disease.A small molecule of β-hydroxybutyrate is a kind of ketone bo...

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11 / 11

2019

Atomic structure of TRPM2 protein is revealed

from EIAab

Scientists at the Van Andel Institute VARI have for the first time revealed the atomic structure of the protein TRPM2, which regulates core body temperature, mediates immune responses, and apoptosis, programmed cell death.TRPM2 is part of the TRP superfamily, which mediates sensory stimuli such as pain, stress, vision,...

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11 / 01

2019

Inhibitory proteins contribute to melanin regeneration in retinal cells

from EIAab

Researchers at the Salk Institute in the United States have determined how certain cells in the eye handle ambient light and reset our biological clock. Late at night, when these cells are exposed to artificial light, our biological clocks can become confusing, leading to a range of health problems.The innermost layer ...

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10 / 30

2019

PIP4 on dispersed trans-Golgi network mediates NLRP3 inflammasome activation

from EIAab

Researchers at the University of Texas Southwestern Medical Center have discovered how DNA can trigger immune and autoimmune responses from within cells by discovering the DNA sensing enzyme cGAS.The NLRP3 protein is the basis for inflammation of a group of autoinflammatory diseases called cryopyrin protein-associated ...

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10 / 23

2019

One Way To Enhance Kidney Self-repair

from EIAab

Researchers at the Case Western Reserve University School of Medicine and the Cleveland University Hospital Medical Center have discovered a way to enhance kidney self-repair. This is a way to save the damaged kidney by reprogramming the self metabolism.The glycolysis process converts glucose into energy, and new resea...

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10 / 21

2019

New targets for prostate cancer is found by RNA-Seq analyses

from EIAab

The Chinese and American research team led by the Roswell Park Cancer Institute s has linked the development of castration-resistant prostate cancer to the lack of androgen receptor expression in prostate cancer cells, identifying new therapeutic targets.Prostate cancer is one of the most common cancers in men and the ...

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09 / 30

2019

A protein that blocks breast cancer signaling

from EIAab

Researchers at Princeton University found that a compound called Tinagl1 blocks both the epidermal growth factor receptor EGFR and integrin pathways and slows the spread of triple-negative breast cancer.The researchers found that Tinagl1 inhibits two major pathways that are helpful for the aggressiveness and drug resis...

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09 / 29

2019

New biomarkers for cancer diagnosis

from EIAab

A new study at Tel Aviv University found that an elevated level of protein called ubiquilin-4 is a new biomarker of genomic instability. The study found that ubiquilin 4 is involved in protecting the genome from DNA damage, while excessive ubiquilin 4 is harmful. When the number of ubiquilin 4 in tumor cells increases,...

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09 / 25

2019

A protein that initiates efficient decomposition of fat

from EIAab

Researchers at the UT Southwestern Medical Center in the United States have discovered that a new role for Perilipin 5, which is usually located on the surface of lipid droplets in cells, acts as a regulator of fat metabolism in the nucleus.In obese people and rodent, excess fat accumulates in tissues that are not spec...

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09 / 24

2019

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