Human LAMP2/ Lysosome-associated membrane glycoprotein 2 CLIA Kit
溶酶体相关膜糖蛋白2

货号:

U1464h

商标:

EIAab^®

监管等级:

RUO

别名:

CD107 antigen-like family member B, LGP-96, CD107b, LAMP-2

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

39-2500pg/mL

特异性:

Natural and recombinant human Lysosome-associated membrane glycoprotein 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cardiovascular

规格 & 价格:

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Human LAMP2 CLIA Kit

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产品说明书

说明书:

MSDS:

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通用注释

亚单元:

Monomer (PubMed:18644871, PubMed:25342746). Homodimer (PubMed:25342746). Homotrimer (PubMed:25342746). Forms large homooligomers (PubMed:18644871). Interacts (via its cytoplasmic region) with HSPA8 (PubMed:25342746). Interacts with HSP90 in the lysosome lumen; this enhances LAMP2 stability (By similarity). Interacts with MLLT11 (PubMed:24880125).

功能:

Isoform LAMP-2C: Modulates chaperone-mediated autophagy. Decreases presentation of endogenous antigens by MHCII. Does not play a role in the presentation of exogenous and membrane-derived antigens by MHCII.

亚细胞位置:

Cell membrane Single-pass type I membrane protein Endosome membrane Single-pass type I membrane protein Lysosome membrane Single-pass type I membrane protein Cytoplasmic vesicle Autophagosome membrane This protein shuttles between lysosomes, endosomes, and the plasma membrane.

数据库链接

UniGene:

Hs.496684

SMR:

P13473

KEGG:

hsa:3920

MIM:

300257

Pfam:

PF01299

Uniprot: