EEF1A1 (基因名), Elongation factor 1-alpha 1 (蛋白名), ef1a1_bovin.
产品名称:
Bovine EEF1A1/ Elongation factor 1-alpha 1 CLIA Kit
延长因子1-α1
货号:
U11476b
商标:
EIAab®
监管等级:
别名:
Elongation factor Tu, Eukaryotic elongation factor 1 A-1, EF-Tu, eEF1A-1, EF-1-alpha-1, EEF1A, EF1A
检测方法:
CLIA
实验类型:
Sandwich
特异性:
Natural and recombinant bovine Elongation factor 1-alpha 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Epigenetics
通用注释
亚单元:
Found in a nuclear export complex with XPO5, EEF1A1, Ran and aminoacylated tRNA. Interacts with PARP1, TXK, XPO5 and KARS. May interact with ERGIC2. Interacts with IFIT1 (via TPR repeats 4-7). Interacts with DLC1, facilitating distribution to the membrane periphery and ruffles upon growth factor stimulation. Interacts with ZPR1; the interaction occurs in a epidermal growth factor (EGF)-dependent manner.
功能:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
亚细胞位置:
Cytoplasm
Nucleus
Nucleus
Nucleolus
Colocalizes with DLC1 at actin-rich regions in the cell periphery. Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens (By similarity).
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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