EEF1A1 (基因名), Elongation factor 1-alpha 1 (蛋白名), ef1a1_human.
产品名称:
Human EEF1A1/ Elongation factor 1-alpha 1 CLIA Kit
延长因子1-α1
货号:
U11476h
商标:
EIAab®
监管等级:
别名:
Elongation factor Tu, Eukaryotic elongation factor 1 A-1, Leukocyte receptor cluster member 7, EF-Tu, eEF1A-1, EF-1-alpha-1, EEF1A, EF1A, LENG7
检测方法:
CLIA
实验类型:
Sandwich
检测范围:
19.5-1250pg/mL
特异性:
Natural and recombinant human Elongation factor 1-alpha 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
Epigenetics
精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: 3.9%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: 7.7%
批内 CV: 3.9%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: 7.7%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。
Sample Type |
Average(%) |
Recovery Range(%) |
Serum |
99 |
91-103 |
Plasma |
98 |
93-106 |
线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。
Sample |
1:2 |
1:4 |
1:8 |
1:16 |
serum(n=5) |
92-105% |
90-101% |
95-105% |
92-109% |
EDTA plasma(n=5) |
89-95% |
93105% |
89-94% |
90-106% |
heparin plasma(n=5) |
93-104%
|
94-110% |
101-111% |
91-110% |
通用注释
亚单元:
Found in a nuclear export complex with XPO5, EEF1A1, Ran and aminoacylated tRNA. Interacts with PARP1, TXK, XPO5 and KARS. May interact with ERGIC2. Interacts with IFIT1 (via TPR repeats 4-7) (By similarity). Interacts with DLC1, facilitating distribution to the membrane periphery and ruffles upon growth factor stimulation. Interacts with ZPR1; the interaction occurs in a epidermal growth factor (EGF)-dependent manner.
功能:
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
亚细胞位置:
Cytoplasm
Nucleus
Nucleus
Nucleolus
Colocalizes with DLC1 at actin-rich regions in the cell periphery. Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens.
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