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IGF2R (基因名), Cation-independent mannose-6-phosphate receptor (蛋白名), MPRI_BOVIN.
产品名称:

Bovine IGF2R/ Cation-independent mannose-6-phosphate receptor Recombinant Protein
CIMan-6-Preceptor

货号:

R1629b

商标:
EIAab®
监管等级:
别名:

300 kDa mannose 6-phosphate receptor, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, MPR 300, IGF-II receptor, CD222, CI Man-6-P receptor, M6P

序列号:
P08169
来源:
E.coli
种属:
Bovine
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Bovine IGF2R Protein
规格 & 价格: cart
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Bovine IGF2R Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts with DPP4; the interaction is direct. Binds GGA1, GGA2 and GGA3 (By similarity). Binds HA-I and HA-II plasma membrane adapters.


功能:
Acts as a positive regulator of T-cell coactivation, by binding DPP4 (By similarity). Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2.


亚细胞位置:
Lysosome membrane Single-pass type I membrane protein Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface.


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