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首页  >  酶联免疫试剂盒  >  Human ABCC11 ELISA Kit
ABCC11 (基因名), ATP-binding cassette sub-family C member 11 (蛋白名), ABCCB_HUMAN.
产品名称:

Human ABCC11/ ATP-binding cassette sub-family C member 11 ELISA Kit
三磷酸腺苷结合盒亚家族C11

货号:

E9625h

商标:
EIAab®
监管等级:
别名:

Multidrug resistance-associated protein 8, MRP8

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.78-50ng/mL
灵敏度:
0.39ng/mL
特异性:
Natural and recombinant human ATP-binding cassette sub-family C member 11
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Human ABCC11 ELISA Kit
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Human ABCC11 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

84-92%

106-116%

96-106%

95-105%

EDTA plasma(n=5)

117-127%

108-117%

107-117%

87-96%

heparin plasma(n=5)

103-114%

 

110-120%

92-92%

105-115%

 

通用注释


亚单元:
N/A


功能:
Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides (PubMed:12764137, PubMed:15537867). Enhances the cellular extrusion of cAMP and cGMP (PubMed:12764137, PubMed:15537867). Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate (PubMed:15537867, PubMed:25896536). Probably functions to secrete earwax (PubMed:16444273, PubMed:19383836). Required for the secretion of components contributing to axillary odor formation (PubMed:19710689).


亚细胞位置:
Cell membrane Multi-pass membrane protein Vacuole membrane Cytoplasmic vesicle membrane


该产品尚未在任何出版物中被引用。

[1].
"Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11)."

[2].
"MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine."

[3].
"Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12."

[4].
"A functional ABCC11 allele is essential in the biochemical formation of human axillary odor."

[5].
"Earwax, osmidrosis, and breast cancer: why does one SNP (538G>A) in the human ABC transporter ABCC11 gene determine earwax type?"

[6].
"Japanese map of the earwax gene frequency: a nationwide collaborative study by Super Science High School Consortium."

[7].
"A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene."

[8].
"A SNP in the ABCC11 gene is the determinant of human earwax type."

[9].
"MRP8, a new member of ABC transporter superfamily, identified by EST database mining and gene prediction program, is highly expressed in breast cancer."

[10].
"Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12."
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