ABCC11 (基因名), ATP-binding cassette sub-family C member 11 (蛋白名), abccb_human.
产品名称:
Human ABCC11/ ATP-binding cassette sub-family C member 11 CLIA Kit
三磷酸腺苷结合盒亚家族C11
货号:
U9625h
商标:
EIAab®
监管等级:
别名:
Multidrug resistance-associated protein 8, MRP8
检测方法:
CLIA
特异性:
Natural and recombinant human ATP-binding cassette sub-family C member 11
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
N/A
功能:
Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides (PubMed:12764137, PubMed:15537867). Enhances the cellular extrusion of cAMP and cGMP (PubMed:12764137, PubMed:15537867). Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate (PubMed:15537867, PubMed:25896536). Probably functions to secrete earwax (PubMed:16444273, PubMed:19383836). Required for the secretion of components contributing to axillary odor formation (PubMed:19710689).
亚细胞位置:
Cell membrane
Multi-pass membrane protein
Vacuole membrane
Cytoplasmic vesicle membrane
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