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Proinsulin (短名 ),
产品名称:

Pig Proinsulin ELISA Kit
胰岛素

货号:

E0379p

商标:
EIAab®
监管等级:
检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.625-40pmol/ml
灵敏度:
0.26pmol/ml
特异性:
Natural and recombinant pig Proinsulin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Signal Transduction
Pig Proinsulin ELISA Kit
规格 & 价格: cart
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Pig Proinsulin ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

103-111%

106-116%

105-113%

112-120%

EDTA plasma(n=5)

87-97%

86-96%

88-96%

96-106%

heparin plasma(n=5)

102-114%

 

82-91%

80-90%

101-111%

 

通用注释


亚单元:
N/A


功能:
Proinsulin is the prohormone precursor to insulin made in the beta cells of the islets of Langerhans, specialized regions of the pancreas. In humans, proinsulin is encoded by the INS gene.


Location:
Proinsulin is synthesized in the endoplasmic reticulum, where it is folded and its disulfide bonds are oxidized. It is then transported to the Golgi apparatus where it is packaged into secretory vesicles, and where it is processed by a series of proteases to form mature insulin. Mature insulin has 35 fewer amino acids; 4 are removed altogether, and the remaining 31 form the C-peptide. The C-peptide is abstracted from the center of the proinsulin sequence; the two other ends (the B chain and A chain) remain connected by disulfide bonds.


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