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Thoc3 (基因名), THO complex subunit 3 (蛋白名), thoc3_mouse.
产品名称:

Mouse Thoc3/ THO complex subunit 3 Recombinant Protein

货号:

R16108m

商标:
EIAab®
监管等级:
别名:

Tho3

序列号:
Q8VE80
来源:
E.coli
种属:
Mouse
标签:
His
序列:
2-351aa
预估分子量:
38.5 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Thoc3 Protein
规格 & 价格: cart
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Mouse Thoc3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
Mouse Thoc3 Protein
Recombinant mouse Thoc3 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
通用注释


亚单元:
Component of the THO complex, which is composed of THOC1, THOC2, THOC3, THOC5, THOC6 and THOC7; together with at least ALYREF/THOC4, DDX39B, SARNP/CIP29 and CHTOP, THO forms the transcription/export (TREX) complex which seems to have a dynamic structure involving ATP-dependent remodeling.


功能:
Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.


亚细胞位置:
Nucleus Nucleus speckle


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