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THOC3 (基因名), THO complex subunit 3 (蛋白名), thoc3_bovin.
产品名称:

Bovine THOC3/ THO complex subunit 3 ELISA Kit

货号:

E16108b

商标:
EIAab®
监管等级:
别名:

Tho3

检测方法:
ELISA
特异性:
Natural and recombinant bovine THO complex subunit 3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Bovine THOC3 ELISA Kit
规格 & 价格: cart
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Bovine THOC3 ELISA Kit
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通用注释


亚单元:
Component of the THO complex, which is composed of THOC1, THOC2, THOC3, THOC5, THOC6 and THOC7; together with at least ALYREF/THOC4, DDX39B, SARNP/CIP29 and CHTOP, THO forms the transcription/export (TREX) complex which seems to have a dynamic structure involving ATP-dependent remodeling.


功能:
Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.


亚细胞位置:
Nucleus Nucleus speckle


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