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B4GALT5 (基因名), Beta-1,4-galactosyltransferase 5 (蛋白名), b4gt5_human.
产品名称:

Human B4GALT5/ Beta-1,4-galactosyltransferase 5 Recombinant Protein
β-1,4半乳糖基转移酶5

货号:

R2493h

商标:
EIAab®
监管等级:
别名:

Beta-1, 4-GalT II, Glucosylceramide beta-1, 4-galactosyltransferase, Lactosylceramide synthase, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 5, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 5, LacCer synthase, Beta-1, 4-GalTase 5

序列号:
O43286
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human B4GALT5 Protein
规格 & 价格: cart
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Human B4GALT5 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 20q13.13 by HGNC 20q13.13 by Entrez Gene 20q13.13 by Ensembl
B4GALT5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (PubMed:24498430). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). Plays a role in the glycosylation of BMPR1A and regulation of its protein stability (By similarity). Essential for extraembryonic development during early embryogenesis (By similarity).


亚细胞位置:
Golgi apparatus Golgi stack membrane Single-pass type II membrane protein Golgi apparatus Trans cisternae of Golgi stack.


该产品尚未在任何出版物中被引用。

[1].
"Molecular cloning of a human cDNA encoding beta-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal:GlcNAc beta-1,4-galactosyltransferase."

[2].
"The expanding beta 4-galactosyltransferase gene family: messages from the databanks."

[3].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[4].
"The DNA sequence and comparative analysis of human chromosome 20."

[5].
"Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions."

[6].
"Architecture of the human interactome defines protein communities and disease networks."

[7].
"RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination."

[8].
"The BioPlex Network: A Systematic Exploration of the Human Interactome."

[9].
"Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium."

[10].
"Proteomic analysis of podocyte exosome-enriched fraction from normal human urine."
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