B4galt5 (基因名), Beta-1,4-galactosyltransferase 5 (蛋白名), b4gt5_mouse.
产品名称:
Mouse B4galt5/ Beta-1,4-galactosyltransferase 5 CLIA Kit
β-1,4半乳糖基转移酶5
货号:
U2493m
商标:
EIAab®
监管等级:
别名:
Beta-1, 4-GalT II, Glucosylceramide beta-1, 4-galactosyltransferase, Lactosylceramide synthase, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 5, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 5, LacCer synthase, Beta-1, 4-GalTase 5, Bgt-5
检测方法:
CLIA
特异性:
Natural and recombinant mouse Beta-1,4-galactosyltransferase 5
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
N/A
功能:
Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (PubMed:21057870, PubMed:23882130, PubMed:30114188). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (PubMed:30114188). Plays a role in the glycosylation of BMPR1A and regulation of its protein stability (PubMed:29415997). Essential for extraembryonic development during early embryogenesis (PubMed:20574042, PubMed:21057870).
亚细胞位置:
Golgi apparatus
Golgi stack membrane
Single-pass type II membrane protein
Golgi apparatus
Trans cisternae of Golgi stack.
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