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ADIPOR1 (基因名), Adiponectin receptor protein 1 (蛋白名), paqr1_human.

产品名称:

ADIPOR1 Antibody

货号:

P2221Rb-h

商标:

EIAab^®

监管等级:

RUO

别名:

Progestin and adipoQ receptor family member 1, Progestin and adipoQ receptor family member I, CGI-45, PAQR1, TESBP1A

序列号:

Q96A54

反应性:

human

免疫原:

Recombinant human ADIPOR1 protein ( R2221h )

形态:

Liquid

存储说明:

4℃ for frequent use, -20℃ to -70℃ for 6 months

缓冲液:

0.1M×PBS,50% glycerol,pH7.5

浓度:

200ug/ml

纯化方式:

Immunogen affinity purified

克隆性:

Polyclonal

亚型:

Rabbit IgG

应用:

推荐产品:

Goat Anti-Rabbit IgG(H+L) HRP-conjugated Antibody

研究领域:

规格 & 价格:

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Human ADIPOR1 Polyclonal Antibody

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产品说明书

数据表:

MSDS:

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R&D 技术数据

Y79 cell was subjected to SDS-PAGE followed by Western Blot with Adiponectin receptor protein 1antibody at dilution of 1:300

Immunohistochemistry of paraffin-embedded human liver tissue using ADIPOR1 antibody at dilution of 1:100

通用注释

亚单元:

May form homooligomers and heterooligomers with ADIPOR2 (PubMed:12802337). Interacts with APPL2 (via BAR domain); hinders the accessibility of APPL1 to ADIPOR1; negatively regulates adiponectin signaling; ADIPOQ dissociates this interaction and facilitates the recruitment of APPL1 to ADIPOR1. Interacts with APPL1; ADIPOQ enhances this interaction; inhibites adiponectin-stimulated binding of APPL2 to ADIPOR1 (By similarity).

功能:

Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:25855295, PubMed:12802337). Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity).

亚细胞位置:

Cell membrane Multi-pass membrane protein Localized to the cell membrane and intracellular organelles.

数据库链接

UniGene:

Hs.5298

SMR:

Q96A54

STRING:

9606.ENSP00000341785

KEGG:

hsa:51094

MIM: