首页 > 重组蛋白 > Human ADIPOR1 Recombinant Protein

ADIPOR1 (基因名), Adiponectin receptor protein 1 (蛋白名), paqr1_human.

产品名称:

Human ADIPOR1/ Adiponectin receptor protein 1 Recombinant Protein
脂联素受体蛋白1

货号:

R2221h

商标:

EIAab^®

监管等级:

RUO

别名:

Progestin and adipoQ receptor family member 1, Progestin and adipoQ receptor family member I, CGI-45, PAQR1, TESBP1A

序列号:

Q96A54

来源:

E.coli

种属:

Human

标签:

His

纯度:

>90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

规格 & 价格:

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

基因位点

Cytogenetic band: 1q32.1 by HGNC 1q32.1 by Entrez Gene 1q32.1 by Ensembl

ADIPOR1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

May form homooligomers and heterooligomers with ADIPOR2 (PubMed:12802337). Interacts with APPL2 (via BAR domain); hinders the accessibility of APPL1 to ADIPOR1; negatively regulates adiponectin signaling; ADIPOQ dissociates this interaction and facilitates the recruitment of APPL1 to ADIPOR1. Interacts with APPL1; ADIPOQ enhances this interaction; inhibites adiponectin-stimulated binding of APPL2 to ADIPOR1 (By similarity).

功能:

Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:25855295, PubMed:12802337). Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity).

亚细胞位置:

Cell membrane Multi-pass membrane protein Localized to the cell membrane and intracellular organelles.

数据库链接

UniGene:

Hs.5298

SMR:

Q96A54

STRING:

9606.ENSP00000341785

KEGG:

hsa:51094

MIM:

607945

Pfam:

PF03006

Uniprot:

Q96A54

相关产品

Mouse Adipor1 ELISA Kit

Mouse Adipor1 CLIA Kit

Mouse Adipor1 Protein

Mouse Adipor1 Polyclonal Antibody

Mouse Adipor1 Monoclonal Antibody

序列长度:

375

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

150:

200:

250:

300:

350:

381:

AAAFVHFYGV | SNLQE FRYG | LEGGCTDDTL | L

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"Gene-nutrient interactions in the metabolic syndrome: single nucleotide polymorphisms in ADIPOQ and ADIPOR1 interact with plasma saturated fatty acids to modulate insulin resistance."

(PMID: 20032495)

[2].

"The association of SNPs in ADIPOQ, ADIPOR1, and ADIPOR2 with insulin sensitivity in a cohort of adolescents and their parents."

(PMID: 19037660)

[3].

"Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts."

(PMID: 19208777)

[4].

"No association between polymorphisms in LEP, LEPR, ADIPOQ, ADIPOR1, or ADIPOR2 and postmenopausal breast cancer risk."

(PMID: 19723917)

[5].

"Associations between glucose tolerance, insulin sensitivity and insulin secretion phenotypes and polymorphisms in adiponectin and adiponectin receptor genes in the Quebec Family Study."

(PMID: 18294218)

[6].

"Variants of the adiponectin and adiponectin receptor 1 genes and breast cancer risk."

(PMID: 18451143)

[7].

"Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer risk."

(PMID: 18827209)

[8].

"Adiponectin and adiponectin receptor gene variants in relation to resting metabolic rate, respiratory quotient, and adiposity-related phenotypes in the Quebec Family Study."

(PMID: 17209173)

[9].

"Adiponectin receptor genes: mutation screening in syndromes of insulin resistance and association studies for type 2 diabetes and metabolic traits in UK populations."

(PMID: 17216283)

[10].

"[Relationship between adiponectin receptor 1 gene -3881T/C variant and glucose metabolism in the Chinese]."

(PMID: 17285539)

[1].

人脂联素受体蛋白1(ADIPOR1)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人脂联素受体蛋白1(ADIPOR1)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人脂联素受体蛋白1(ADIPOR1)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人脂联素受体蛋白1(ADIPOR1)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人脂联素受体蛋白1(ADIPOR1)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人脂联素受体蛋白1(ADIPOR1)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人脂联素受体蛋白1(ADIPOR1)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人脂联素受体蛋白1(ADIPOR1)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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