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Tafa5 (基因名), Chemokine-like protein TAFA-5 (蛋白名), tafa5_mouse.
产品名称:

Mouse Tafa5/ Chemokine-like protein TAFA-5 ELISA Kit
FAM19A5蛋白

货号:

E6694m

商标:
EIAab®
监管等级:
别名:

Fam19a5

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.469-30ng/mL
灵敏度:
0.23ng/mL
特异性:
Natural and recombinant mouse Chemokine-like protein TAFA-5
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Mouse Tafa5 ELISA Kit
规格 & 价格: cart
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Mouse Tafa5 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
N/A


功能:
Acts as a chemokine-like protein by regulating cell proliferation and migration through activation of G protein-coupled receptors (GPCRs), such as S1PR2 and FPR2 (PubMed:29453251, PubMed:29138422). Stimulates chemotactic migration of macrophages mediated by the MAPK3/ERK1 and AKT1 pathway (PubMed:29138422). Blocks TNFSF11/RANKL-induced osteoclast formation from macrophages by inhibiting up-regulation of osteoclast fusogenic and differentiation genes (PubMed:29138422). Stimulation of macrophage migration and inhibition of osteoclast formation is mediated through the GPCR FPR2 (PubMed:29138422). Acts as an adipokine by negatively regulating vascular smooth muscle cell (VSMC) proliferation and migration in response to platelet-derived growth factor stimulation via GPCR S1PR2 and G protein GNA12/GNA13-transmitted RHOA signaling (By similarity). Inhibits injury-induced cell proliferation and neointima formation in the femoral arteries (PubMed:29453251).


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。
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