Bovine TAFA5/ Chemokine-like protein TAFA-5 CLIA Kit
FAM19A5蛋白

货号:

U6694b

商标:

EIAab^®

监管等级:

RUO

别名:

FAM19A5

检测方法:

CLIA

特异性:

Natural and recombinant bovine Chemokine-like protein TAFA-5

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Bovine TAFA5 CLIA Kit

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产品说明书

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通用注释

亚单元:

N/A

功能:

Acts as a chemokine-like protein by regulating cell proliferation and migration through activation of G protein-coupled receptors (GPCRs), such as S1PR2 and FPR2 (By similarity). Stimulates chemotactic migration of macrophages mediated by the MAPK3/ERK1 and AKT1 pathway (By similarity). Blocks TNFSF11/RANKL-induced osteoclast formation from macrophages by inhibiting up-regulation of osteoclast fusogenic and differentiation genes (By similarity). Stimulation of macrophage migration and inhibition of osteoclast formation is mediated through the GPCR FPR2 (By similarity). Acts as an adipokine by negatively regulating vascular smooth muscle cell (VSMC) proliferation and migration in response to platelet-derived growth factor stimulation via GPCR S1PR2 and G protein GNA12/GNA13-transmitted RHOA signaling (By similarity). Inhibits injury-induced cell proliferation and neointima formation in the femoral arteries (By similarity).

亚细胞位置:

Secreted

数据库链接

UniGene:

Bt.66476

KEGG:

bta:767927

Pfam:

PF12020

Uniprot:

Q3ZBS2