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SARM1 (基因名), Sterile alpha and TIR motif-containing protein 1 (蛋白名), sarm1_pig.
产品名称:

Pig SARM1/ Sterile alpha and TIR motif-containing protein 1 ELISA Kit

货号:

E15733p

商标:
EIAab®
监管等级:
别名:

Tir-1 homolog

检测方法:
ELISA
特异性:
Natural and recombinant pig Sterile alpha and TIR motif-containing protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Pig SARM1 ELISA Kit
规格 & 价格: cart
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Pig SARM1 ELISA Kit
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通用注释


亚单元:
Interacts with TICAM1/TRIF and thereby interferes with TICAM1/TRIF function. Interacts with MAPK10/JNK3 and SDC2 (via cytoplasmic domain).


功能:
Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration, an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38.


亚细胞位置:
Cytoplasm Cell projection Axon Cell projection Dendrite Cell junction Synapse Mitochondrion Associated with microtubules.


该产品尚未在任何出版物中被引用。
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