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IL12B (基因名), Interleukin-12 subunit beta (蛋白名), il12b_canlf.
产品名称:

Dog IL12B/ Interleukin-12 subunit beta ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, CLMF p40, IL-12B

检测方法:
ELISA
特异性:
Natural and recombinant dog Interleukin-12 subunit beta
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Immunology
Dog IL12B ELISA Kit
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Dog IL12B ELISA Kit
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通用注释


亚单元:
Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12. Heterodimer with IL23A; disulfide-linked. The heterodimer is known as interleukin IL-23. Also secreted as a monomer.


功能:
Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。
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