Human IL12B/ Interleukin-12 subunit beta CLIA Kit
白介素12B

货号:

U0058h

商标:

EIAab^®

监管等级:

RUO

别名:

Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, NK cell stimulatory factor chain 2, CLMF p40, NKSF2, IL-12B, NKSF2

检测方法:

CLIA

实验类型:

Sandwich

检测范围:

3.9-250pg/mL

特异性:

Natural and recombinant human Interleukin-12 subunit beta

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Immunology

规格 & 价格:

关注

Human IL12B CLIA Kit

邮箱 *

消息 *

Please 登录.

产品说明书

说明书:

MSDS:

在线询价

数据
文献
序列 / 3D
反馈墙 (0)

通用注释

亚单元:

Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12. Heterodimer with IL23A; disulfide-linked. The heterodimer is known as interleukin IL-23. Also secreted as a monomer.

功能:

Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

亚细胞位置:

Secreted

数据库链接

UniGene:

Hs.674

SMR:

P29460

STRING:

9606.ENSP00000231228

KEGG:

hsa:3593

MIM: