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INPP5B (基因名), Type II inositol 1,4,5-trisphosphate 5-phosphatase (蛋白名), i5p2_human.
产品名称:

Human INPP5B/ Type II inositol 1,4,5-trisphosphate 5-phosphatase ELISA Kit

货号:

E2815h

商标:
EIAab®
监管等级:
别名:

75 kDa inositol polyphosphate-5-phosphatase, Phosphoinositide 5-phosphatase, 5PTase, OCRL2

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/mL
灵敏度:
26pg/mL
特异性:
Natural and recombinant human Type II inositol 1,4,5-trisphosphate 5-phosphatase
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cardiovascular
Human INPP5B ELISA Kit
规格 & 价格: cart
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Human INPP5B ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Interacts with APPL1, FAM109A and FAM109B. Interacts with several Rab GTPases, at least RAB1A, RAB2A, RAB5A, RAB6A, RAB8A, RAB9A and RAB33B; these interactions may play a dual role in targeting INPP5B to the specific membranes and stimulating the phosphatase activity. Interacts with INPP5F (PubMed:25869668).


功能:
Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5-trisphosphate (PtIns(1,4,5)P3), and thereby modulates cellular signaling events.


亚细胞位置:
Cytoplasm Cytosol Endoplasmic reticulum-Golgi intermediate compartment Early endosome membrane Membrane Peripheral membrane protein Cytoplasmic side Cytoplasmic vesicle Phagosome membrane Golgi apparatus


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