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Inpp5b (基因名), Type II inositol 1,4,5-trisphosphate 5-phosphatase (蛋白名), i5p2_mouse.

产品名称:

Mouse Inpp5b/ Type II inositol 1,4,5-trisphosphate 5-phosphatase CLIA Kit

货号:

U2815m

商标:

EIAab^®

监管等级:

RUO

别名:

Inositol polyphosphate-5-phosphatase B, Phosphoinositide 5-phosphatase, 5PTase

检测方法:

CLIA

特异性:

Natural and recombinant mouse Type II inositol 1,4,5-trisphosphate 5-phosphatase

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cardiovascular

规格 & 价格:

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通用注释

亚单元:

Interacts with APPL1, FAM109A and FAM109B. Interacts with several Rab GTPases, at least RAB1A, RAB2A, RAB5A, RAB6A, RAB8A, RAB9A and RAB33B; these interactions may play a dual role in targeting INPP5B to the specific membranes and stimulating the phosphatase activity (By similarity). Interacts with INPP5F (PubMed:25869668).

功能:

Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5-trisphosphate (PtIns(1,4,5)P3), and thereby modulates cellular signaling events.

亚细胞位置:

Cytoplasm Cytosol Endoplasmic reticulum-Golgi intermediate compartment Early endosome membrane Membrane Peripheral membrane protein Cytoplasmic side Cytoplasmic vesicle Phagosome membrane

数据库链接

UniGene:

Mm.296202

SMR:

Q8K337

STRING:

10090.ENSMUSP00000092375

KEGG:

mmu:16330

Pfam:

PF03372

Uniprot: