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CASP1 (基因名), Caspase-1 (蛋白名), casp1_horse.
产品名称:

Horse CASP1/ Caspase-1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45, IL-1BC, ICE, CASP-1, IL1BC

检测方法:
ELISA
特异性:
Natural and recombinant horse Caspase-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Neurosciences
Horse CASP1 ELISA Kit
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Horse CASP1 ELISA Kit
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通用注释


亚单元:
Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 20 kDa (p20) and a 10 kDa (p10) subunit. The p20 subunit can also form a heterodimer with the epsilon isoform which then has an inhibitory effect. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and NALP2 and whose function would be the activation of proinflammatory caspases. Both the p10 and p20 subunits interact with MEFV. Interacts with CARD17/INCA and CARD18.


功能:
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.


亚细胞位置:
Cytoplasm


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