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Casp1 (基因名), Caspase-1 (蛋白名), casp1_mouse.
产品名称:

Mouse Casp1/ Caspase-1 ELISA Kit
半胱天冬酶1

货号:

E1592m

商标:
EIAab®
监管等级:
别名:

Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45, IL-1BC, ICE, CASP-1, Il1bc

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/mL
灵敏度:
41.4pg/mL
特异性:
Natural and recombinant mouse Caspase-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Neurosciences
Mouse Casp1 ELISA Kit
规格 & 价格: cart
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Mouse Casp1 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 20 kDa (p20) and a 10 kDa (p10) subunit. The p20 subunit can also form a heterodimer with the epsilon isoform which then has an inhibitory effect. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and NALP2 and whose function would be the activation of proinflammatory caspases. Both the p20 and p10 subunits interact with MEFV (By similarity). Interacts with CARD17/INCA and CARD18.


功能:
Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.


亚细胞位置:
Cytoplasm


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