Was (基因名), Wiskott-Aldrich syndrome protein homolog (蛋白名), wasp_mouse.
产品名称:
Mouse Was/ Wiskott-Aldrich syndrome protein homolog CLIA Kit
Wiskott-Aldrich综合症蛋白质
货号:
U1917m
商标:
EIAab®
监管等级:
别名:
WASp, Wasp
检测方法:
CLIA
特异性:
Natural and recombinant mouse Wiskott-Aldrich syndrome protein homolog
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Interacts with CDC42, RAC, NCK, FYN, HCK, SRC kinase FGR, BTK, ABL1, PSTPIP1, WIP, and to the p85 subunit of PLC-gamma. Binds the Arp2/3 complex. Interacts (via C-terminus) with ALDOA (By similarity). Interacts with NCK1 (via SH3 domains).
功能:
Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.
亚细胞位置:
Cytoplasm
Cytoskeleton
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