Human WAS/ Wiskott-Aldrich syndrome protein CLIA Kit
Wiskott-Aldrich综合症蛋白质

货号:

U1917h

商标:

EIAab^®

监管等级:

RUO

别名:

WASp, IMD2

检测方法:

CLIA

特异性:

Natural and recombinant human Wiskott-Aldrich syndrome protein

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Human WAS CLIA Kit

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通用注释

亚单元:

Interacts with NCK1 (via SH3 domains) (By similarity). Interacts with CDC42, RAC, NCK, HCK, FYN, SRC kinase FGR, BTK, ABL1, PSTPIP1, WIP, and to the p85 subunit of PLC-gamma. Binds the Arp2/3 complex. Interacts (via C-terminus) with ALDOA. Interacts with E.coli effector protein EspF(U).

功能:

Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.

亚细胞位置:

Cytoplasm Cytoskeleton

数据库链接

UniGene:

Hs.2157

SMR:

P42768

STRING:

9606.ENSP00000365891

KEGG:

hsa:7454

MIM: