RAB10 (基因名), Ras-related protein Rab-10 (蛋白名), rab10_chick.
产品名称:
Chicken RAB10/ Ras-related protein Rab-10 CLIA Kit
Ras相关蛋白Rab-10
货号:
U5608c
商标:
EIAab®
监管等级:
别名:
RCJMB04_23k10
检测方法:
CLIA
实验类型:
Sandwich
特异性:
Natural and recombinant chicken Ras-related protein Rab-10
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
登录.
研究领域:
Signal Transduction
通用注释
亚单元:
N/A
功能:
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Plays also a specific role in asymmetric protein transport to the plasma membrane within the polarized neuron and epithelial cells. In neurons, it is involved in axonogenesis through regulation of vesicular membrane trafficking toward the axonal plasma membrane while in epithelial cells, it regulates transport from the Golgi to the basolateral membrane. Moreover, may play a role in the basolateral recycling pathway and in phagosome maturation. Finally, may play a role in endoplasmic reticulum dynamics and morphology controlling tubulation along microtubules and tubules fusion.
亚细胞位置:
Cytoplasmic vesicle membrane
Lipid-anchor
Cytoplasmic side
Golgi apparatus
Trans-Golgi network membrane
Endosome membrane
Recycling endosome membrane
Cytoplasmic vesicle
Phagosome membrane
Cell projection
Cilium
Endoplasmic reticulum membrane
Associates with SLC2A4/GLUT4 storage vesicles (By similarity). Localizes to the base of the cilium (By similarity). Transiently associates with phagosomes (By similarity). Localizes to the endoplasmic reticulum at domains of new tubule growth (By similarity).
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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