Kiss1 (基因名), Metastasis-suppressor KiSS-1 (蛋白名), kiss1_mouse.
产品名称:
Mouse Kiss1/ Metastasis-suppressor KiSS-1 CLIA Kit
肿瘤转移抑制基因KISS-1
货号:
U2063m
商标:
EIAab®
监管等级:
别名:
Kisspeptin-1
检测方法:
CLIA
特异性:
Natural and recombinant mouse Metastasis-suppressor KiSS-1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
N/A
功能:
Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. Intracerebroventricular administration induces an increase in serum LH and FSH levels in prepubertal male and female as well as in adult animals.
亚细胞位置:
Secreted
数据库链接
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
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