Kat7 (基因名), Histone acetyltransferase KAT7 (蛋白名), kat7_rat.
产品名称:
Rat Kat7/ Histone acetyltransferase KAT7 CLIA Kit
货号:
U2935r
商标:
EIAab®
监管等级:
别名:
Histone acetyltransferase binding to ORC1, Lysine acetyltransferase 7, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, MYST-2, Hbo1, Myst2
检测方法:
CLIA
特异性:
Natural and recombinant rat Histone acetyltransferase KAT7
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
-
通用注释
亚单元:
Component of the HBO1 complex composed at least of ING4 or ING5, KAT7/HBO1, MEAF6, and one of JADE1, JADE2 and JADE3. Interacts with MCM2 and ORC1. Interacts with the androgen receptor (AR) in the presence of dihydrotestosterone. Interacts with CDT1.
功能:
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Acts as a coactivator of the licensing factor CDT1. Specifically represses AR-mediated transcription.
亚细胞位置:
Nucleus
Nucleoplasm
Associates with replication origins specifically during the G1 phase of the cell cycle.
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