Mouse Kat7/ Histone acetyltransferase KAT7 CLIA Kit

货号:

U2935m

商标:

EIAab^®

监管等级:

RUO

别名:

Histone acetyltransferase binding to ORC1, Lysine acetyltransferase 7, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, MYST-2, Hbo1, Myst2

检测方法:

CLIA

特异性:

Natural and recombinant mouse Histone acetyltransferase KAT7

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Mouse Kat7 CLIA Kit

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通用注释

亚单元:

Component of the HBO1 complex composed at least of ING4 or ING5, KAT7/HBO1, MEAF6, and one of JADE1, JADE2 and JADE3. Interacts with MCM2 and ORC1. Interacts with the androgen receptor (AR) in the presence of dihydrotestosterone. Interacts with CDT1.

功能:

Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Acts as a coactivator of the licensing factor CDT1. Specifically represses AR-mediated transcription.

亚细胞位置:

Nucleus Nucleoplasm Associates with replication origins specifically during the G1 phase of the cell cycle.

数据库链接

UniGene:

Mm.472268

SMR:

Q5SVQ0

STRING:

10090.ENSMUSP00000103362

KEGG:

mmu:217127

Pfam: