Rat Il1rl2/ Interleukin-1 receptor-like 2 CLIA Kit
Interleukin-1受体2

货号:

U15234r

商标:

EIAab^®

监管等级:

RUO

别名:

IL-36 receptor, Interleukin-1 receptor-related protein 2, IL-1Rrp2

检测方法:

CLIA

特异性:

Natural and recombinant rat Interleukin-1 receptor-like 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

关注

Rat Il1rl2 CLIA Kit

邮箱 *

消息 *

Please 登录.

产品说明书

在线询价

数据
文献
序列 / 3D
反馈墙 (0)

通用注释

亚单元:

Interacts with IL1RAP; the association is enhanced by IL36B indicative for an functional signaling complex and inhibited by IL36RN.

功能:

Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway. Receptor for the interleukin IL36G. Binding to the agonist leads to the activation of NF-kappa-B.

亚细胞位置:

Membrane Single-pass type I membrane protein

数据库链接

UniGene:

Rn.10235

SMR:

Q62929

STRING:

10116.ENSRNOP00000019880

KEGG:

rno:171106

Pfam: