Mouse Il1rl2/ Interleukin-1 receptor-like 2 CLIA Kit
Interleukin-1受体2

货号:

U15234m

商标:

EIAab^®

监管等级:

RUO

别名:

IL-36 receptor, Interleukin-1 receptor-related protein 2, IL-1Rrp2

检测方法:

CLIA

特异性:

Natural and recombinant mouse Interleukin-1 receptor-like 2

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

规格 & 价格:

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Mouse Il1rl2 CLIA Kit

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通用注释

亚单元:

Interacts with IL1RAP; the association is enhanced by IL36B indicative for an functional signaling complex and inhibited by IL36RN.

功能:

Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.

亚细胞位置:

Membrane Single-pass type I membrane protein

数据库链接

UniGene:

Mm.155583

STRING:

10090.ENSMUSP00000092630

KEGG:

mmu:107527

Pfam:

PF13895

Uniprot: