Rat Ido1/ Indoleamine 2,3-dioxygenase 1 CLIA Kit
吲哚胺2,3-双加氧酶1

货号:

U1547r

商标:

EIAab^®

监管等级:

RUO

别名:

Indoleamine-pyrrole 2, 3-dioxygenase, IDO-1, Ido, Indo

检测方法:

CLIA

特异性:

Natural and recombinant rat Indoleamine 2,3-dioxygenase 1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Cell Biology

规格 & 价格:

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Rat Ido1 CLIA Kit

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产品说明书

在线询价

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通用注释

亚单元:

Monomer.

功能:

Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway. Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses. Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells. Acts as a suppressor of anti-tumor immunity. Limits the growth of intracellular pathogens by depriving tryptophan. Protects the fetus from maternal immune rejection.

亚细胞位置:

Cytoplasm Cytosol

数据库链接

UniGene:

Rn.64513

SMR:

Q9ERD9

STRING:

10116.ENSRNOP00000050320

KEGG:

rno:66029

Pfam: