Hdac9 (基因名), Histone deacetylase 9 (蛋白名), hdac9_mouse.
产品名称:
Mouse Hdac9/ Histone deacetylase 9 CLIA Kit
组蛋白脱乙酰酶9
货号:
U11380m
商标:
EIAab®
监管等级:
别名:
Histone deacetylase 7B, Histone deacetylase-related protein, MEF2-interacting transcription repressor MITR, HD7b, HD9, Hdac7b, Hdrp, Mitr
检测方法:
CLIA
特异性:
Natural and recombinant mouse Histone deacetylase 9
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cancer
通用注释
亚单元:
Homodimer. Interacts with ETV6 (By similarity). Interacts with MEF2, HDAC1, HDAC3, HDAC4, HDAC5, CTBP1 and MAPK10. The phosphorylated form interacts with 14-3-3. Interacts with FOXP3 in the absence of T-cell stimulation.
功能:
Devoided of intrinsic deacetylase activity, promotes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) by recruiting HDAC1 and HDAC3. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription, inhibits skeletal myogenesis and may be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter.
亚细胞位置:
Nucleus
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