hdac9 (基因名), Histone deacetylase 9 (蛋白名), hdac9_chick.
通用注释
亚单元:
Homodimer. Interacts with mef2.
功能:
Devoided of intrinsic deacetylase activity, promotes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) by recruiting other histone deacetylases. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription.
亚细胞位置:
Nucleus
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