GABBR1 (基因名), Gamma-aminobutyric acid type B receptor subunit 1 (蛋白名), gabr1_human.
产品名称:
Human GABBR1/ Gamma-aminobutyric acid type B receptor subunit 1 CLIA Kit
γ氨基丁酸B型受体亚型1
货号:
U2151h
商标:
EIAab®
监管等级:
别名:
GABA-B receptor 1, GPRC3A
检测方法:
CLIA
特异性:
Natural and recombinant human Gamma-aminobutyric acid type B receptor subunit 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
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研究领域:
Cell Biology
通用注释
亚单元:
Heterodimer of GABBR1 and GABBR2. Homodimers may form, but are inactive. Isoform 1E (without C-terminal intracellular domain) is unable to dimerize via a coiled-coil interaction with GABBR2. Interacts with the leucine zipper of the C-terminal bZIP domain of ATF4 via its C-terminal region. Interacts with JAKMIP1.
功能:
Isoform 1E may regulate the formation of functional GABBR1/GABBR2 heterodimers by competing for GABBR2 binding. This could explain the observation that certain small molecule ligands exhibit differential affinity for central versus peripheral sites.
亚细胞位置:
Isoform 1E
Secreted
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