Mouse Bcl2l1/ Bcl-2-like protein 1 CLIA Kit
Bcl2-L-1

货号:

U15265m

商标:

EIAab^®

监管等级:

RUO

别名:

Apoptosis regulator Bcl-X, Bcl2-L-1, Bcl2l, Bclx

检测方法:

CLIA

特异性:

Natural and recombinant mouse Bcl-2-like protein 1

样品类型:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

样品数据:

研究领域:

Neurosciences

规格 & 价格:

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Mouse Bcl2l1 CLIA Kit

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产品说明书

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通用注释

亚单元:

Homodimer. Isoform Bcl-X(L) forms heterodimers with BAX, BAK or BCL2. Heterodimerization with BAX does not seem to be required for anti-apoptotic activity. Interacts with BAD. Interacts (isoform Bcl-X(L)) with SIVA1 (isoform 1); the interaction inhibits the anti-apoptotic activity. Interacts with BECN1 and PGAM5. Isoform Bcl-X(L) interacts with IKZF3. Interacts with HEBP2. Isoform Bcl-X(L) interacts with BOP. Interacts with p53/TP53 and BBC3; interaction with BBC3 disrupts the interaction with p53/TP53. Isoform Bcl-X(L) interacts with DNM1L and CLTA; DNM1L and BCL2L1 isoform BCL-X(L) may form a complex in synaptic vesicles that also contains clathrin and MFF. Interacts with ATP5A and ATP5B; the interactions mediate the association of isoform Bcl-X(L) with the mitochondrial membrane ATP synthase F(1)F(0) ATP synthase (By similarity). Interacts with VDAC1 (By similarity). Isoform Bcl-X(L) interacts (via the loop between motifs BH4 and BH3) with NLRP1 (via LRR repeats), but not with NLRP2, NLRP3, NLRP4, PYCARD, nor MEFV. Interacts with BCL2L11 (via BH3) (PubMed:27013495, PubMed:14499110).

功能:

Isoform Bcl-X(S) promotes apoptosis.

亚细胞位置:

Isoform Bcl-X(delta-TM) Cytoplasm

数据库链接

UniGene:

Mm.238213

SMR:

Q64373

STRING:

10090.ENSMUSP00000007803

KEGG: