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首页  >  化学发光试剂盒  >  Pig Proinsulin CLIA Kit
Proinsulin (短名 ),
产品名称:

Pig Proinsulin CLIA Kit
胰岛素

货号:

U0379p

商标:
EIAab®
监管等级:
检测方法:
CLIA
特异性:
Natural and recombinant pig Proinsulin
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Signal Transduction
Pig Proinsulin CLIA Kit
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产品说明书


通用注释


Sub Unit:
N/A


Function:
Proinsulin is the prohormone precursor to insulin made in the beta cells of the islets of Langerhans, specialized regions of the pancreas. In humans, proinsulin is encoded by the INS gene.


Location:
Proinsulin is synthesized in the endoplasmic reticulum, where it is folded and its disulfide bonds are oxidized. It is then transported to the Golgi apparatus where it is packaged into secretory vesicles, and where it is processed by a series of proteases to form mature insulin. Mature insulin has 35 fewer amino acids; 4 are removed altogether, and the remaining 31 form the C-peptide. The C-peptide is abstracted from the center of the proinsulin sequence; the two other ends (the B chain and A chain) remain connected by disulfide bonds.


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