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BAG6 (基因名), Large proline-rich protein BAG6 (蛋白名), bag6_human.
产品名称:

Human BAG6/ Large proline-rich protein BAG6 Recombinant Protein
大号富含脯氨酸蛋白BAG6

货号:

R14404h

商标:
EIAab®
监管等级:
别名:

BAG family molecular chaperone regulator 6, BCL2-associated athanogene 6, HLA-B-associated transcript 3, Protein G3, Protein Scythe, BAG-6, BAT3, G3

序列号:
P46379
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human BAG6 Protein
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Human BAG6 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 6p21.33 by HGNC 6p21.33 by Entrez Gene 6p21.33 by Ensembl
BAG6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
(Microbial infection) Interacts with L. pneumophila Lpg2160 and LegU1 proteins.


功能:
Mediates ricin-induced apoptosis.


亚细胞位置:
Cytoplasm Cytosol Nucleus Secreted Exosome Normally localized in cytosol and nucleus, it can also be released extracellularly, in exosomes, by tumor and myeloid dendritic cells.



[1].
"A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain."

[2].
"Human leukocyte antigen-B-associated transcript 3 is released from tumor cells and engages the NKp30 receptor on natural killer cells."

[3].
"Structural basis for regulation of the nucleo-cytoplasmic distribution of Bag6 by TRC35."

[4].
"Structural and functional insights into the E3 ligase, RNF126."

[5].
"Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domain."

[6].
"Proteasomal degradation of preemptive quality control (pQC) substrates is mediated by an AIRAPL-p97 complex."

[7].
"Pre-emptive Quality Control Protects the ER from Protein Overload via the Proximity of ERAD Components and SRP."

[8].
"Structure of a BAG6 (Bcl-2-associated athanogene 6)-Ubl4a (ubiquitin-like protein 4a) complex reveals a novel binding interface that functions in tail-anchored protein biogenesis."

[9].
"Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6."

[10].
"USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation."
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