C5 (基因名), Complement C5 (蛋白名), co5_rat.
通用注释
亚单元:
The C5a anaphylatoxin interacts with C5AR1.
功能:
Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
亚细胞位置:
Secreted
[1].
YH Li, H Jin, JS Xu, GQ Guo, DL Chen, Y Bo
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