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首页  >  重组蛋白  >  Human ZYX Recombinant Protein
ZYX (基因名), Zyxin (蛋白名), zyx_human.
产品名称:

Human ZYX/ Zyxin Recombinant Protein
Zyxin

货号:

R15233h

商标:
EIAab®
监管等级:
别名:

Zyxin-2

序列号:
Q15942
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Epigenetics
Human ZYX Protein
规格 & 价格: cart
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Human ZYX Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 7q34 by HGNC 7q34 by Entrez Gene 7q34 by Ensembl
ZYX Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with HPV type 6 protein E6. Does not interact significantly with E6 proteins from HPV types 11, 16, or 18. Interacts, via the Pro-rich regions, with the EVH1 domains of ENAH, EVL and VASP. Interacts with the first LIM domain of TES. Interacts with NEBL (isoform 2). Interacts with SYNPO2.


功能:
Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.


亚细胞位置:
Cytoplasm Cytoplasm Cytoskeleton Nucleus Cell junction Focal adhesion Associates with the actin cytoskeleton near the adhesion plaques. Enters the nucleus in the presence of HESX1.


该产品尚未在任何出版物中被引用。

[1].
"Molecular characterization of human zyxin."

[2].
"The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions."

[3].
"Interaction of zyxin, a focal adhesion protein, with the e6 protein from human papillomavirus type 6 results in its nuclear translocation."

[4].
"Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins."

[5].
"A zyxin-related protein whose synthesis is reduced in virally transformed fibroblasts."

[6].
"Synemin interacts with the LIM domain protein zyxin and is essential for cell adhesion and migration."

[7].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[8].
"Zyxin is a novel interacting partner for SIRT1."

[9].
"Zyxin is involved in thrombin signaling via interaction with PAR-1 receptor."

[10].
"The LIM-domain protein Zyxin binds the homeodomain factor Xanf1/Hesx1 and modulates its activity in the anterior neural plate of Xenopus laevis embryo."
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