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ICAM2 (基因名), Intercellular adhesion molecule 2 (蛋白名), icam2_human.
产品名称:

Human ICAM2/ Intercellular adhesion molecule 2 Recombinant Protein
细胞间粘附分子2

货号:

R0534h

商标:
EIAab®
监管等级:
别名:

CD102, ICAM-2

序列号:
P13598
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ICAM2 Protein
规格 & 价格: cart
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Human ICAM2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 17q23.3 by HGNC 17q23.3 by Entrez Gene 17q23.3 by Ensembl
ICAM2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.


亚细胞位置:
Membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。

[1].
"The human ICAM2 gene maps to 17q23-25."

[2].
"Risk of meningioma and common variation in genes related to innate immunity."

[3].
"Polymorphisms in innate immunity genes and risk of childhood leukemia."

[4].
"Epithelial ICAM-1 and ICAM-2 regulate the egression of human T cells across the bronchial epithelium."

[5].
"Expression of intercellular adhesion molecule (ICAM)-1 or ICAM-2 is critical in determining sensitivity of pancreatic cancer cells to cytolysis by human gammadelta-T cells: implications in the design of gammadelta-T-cell-based immunotherapies for pancreatic cancer."

[6].
"DC-SIGN mediates adhesion and rolling of dendritic cells on primary human umbilical vein endothelial cells through LewisY antigen expressed on ICAM-2."

[7].
"ICAM-2 expression mediates a membrane-actin link, confers a nonmetastatic phenotype and reflects favorable tumor stage or histology in neuroblastoma."

[8].
"alpha-Chain phosphorylation of the human leukocyte CD11b/CD18 (Mac-1) integrin is pivotal for integrin activation to bind ICAMs and leukocyte extravasation."

[9].
"Towards endothelial cell-specific transgene expression in pigs: characterization of the pig ICAM-2 promoter."

[10].
"Contribution of N-linked glycans to the conformation and function of intercellular adhesion molecules (ICAMs)."
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