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ZMPSTE24 (基因名), CAAX prenyl protease 1 homolog (蛋白名), face1_human.
产品名称:

Human ZMPSTE24/ CAAX prenyl protease 1 homolog Recombinant Protein
CAAX prenyl蛋白酶1同源物

货号:

R10840h

商标:
EIAab®
监管等级:
别名:

Farnesylated proteins-converting enzyme 1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog, FACE-1, FACE1, STE24

序列号:
O75844
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ZMPSTE24 Protein
规格 & 价格: cart
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Human ZMPSTE24 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1p34.2 by HGNC 1p34.2 by Entrez Gene 1p34.2 by Ensembl
ZMPSTE24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C.


亚细胞位置:
Endoplasmic reticulum membrane Multi-pass membrane protein Nucleus inner membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins."

[2].
"Dual roles for Ste24p in yeast a-factor maturation: NH2-terminal proteolysis and COOH-terminal CAAX processing."

[3].
"Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study."

[4].
"Severe mandibuloacral dysplasia caused by novel compound heterozygous ZMPSTE24 mutations in two Japanese siblings."

[5].
"A homozygous ZMPSTE24 null mutation in combination with a heterozygous mutation in the LMNA gene causes Hutchinson-Gilford progeria syndrome (HGPS): insights into the pathophysiology of HGPS."

[6].
"Focal segmental glomerulosclerosis in patients with mandibuloacral dysplasia owing to ZMPSTE24 deficiency."

[7].
"Lamin A and ZMPSTE24 (FACE-1) defects cause nuclear disorganization and identify restrictive dermopathy as a lethal neonatal laminopathy."

[8].
"Zinc metalloproteinase, ZMPSTE24, is mutated in mandibuloacral dysplasia."

[9].
"The structural basis of ZMPSTE24-dependent laminopathies."

[10].
"Novel frameshifting mutations of the ZMPSTE24 gene in two siblings affected with restrictive dermopathy and review of the mutations described in the literature."
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