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BID (基因名), BH3-interacting domain death agonist (蛋白名), bid_human.
产品名称:

Human BID/ BH3-interacting domain death agonist Recombinant Protein
BH3结构域凋亡诱导蛋白

货号:

R0629h

商标:
EIAab®
监管等级:
别名:

p22 BID, BID

序列号:
P55957
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human BID Protein
规格 & 价格: cart
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Human BID Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 22q11.21 by HGNC 22q11.21 by Entrez Gene 22q11.21 by Ensembl
BID Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein Bcl-2 (By similarity). p15 BID interacts with ITCH.


功能:
The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.


亚细胞位置:
Isoform 2 Mitochondrion membrane A significant proportion of isoform 2 localizes to mitochondria, it may be cleaved constitutively.


该产品尚未在任何出版物中被引用。

[1].
"Three novel Bid proteins generated by alternative splicing of the human Bid gene."

[2].
"The gene for death agonist BID maps to the region of human 22q11.2 duplicated in cat eye syndrome chromosomes and to mouse chromosome 6."

[3].
"BID: a novel BH3 domain-only death agonist."

[4].
"PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer."

[5].
"TNF superfamily gene polymorphism as prognostic factor in early breast cancer."

[6].
"Activity of protein kinase CK2 uncouples Bid cleavage from caspase-8 activation."

[7].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[8].
"A Large-scale genetic association study of esophageal adenocarcinoma risk."

[9].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[10].
"Germline variation in apoptosis pathway genes and risk of non-Hodgkin's lymphoma."
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