首页 > 重组蛋白 > Human ADCY10 Recombinant Protein

ADCY10 (基因名), Adenylate cyclase type 10 (蛋白名), adcya_human.

产品名称:

Human ADCY10/ Adenylate cyclase type 10 Recombinant Protein
腺苷酸环化酶10

货号:

R1348h

商标:

EIAab^®

监管等级:

RUO

别名:

AH-related protein, Adenylate cyclase homolog, Germ cell soluble adenylyl cyclase, Testicular soluble adenylyl cyclase, hsAC, SAC

序列号:

Q96PN6

来源:

E.coli

种属:

Human

标签:

His

纯度:

>90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

规格 & 价格:

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Human ADCY10 Protein

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

基因位点

Cytogenetic band: 1q24.2 by HGNC 1q24.2 by Entrez Gene 1q24.2 by Ensembl

ADCY10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

N/A

功能:

Catalyzes the formation of the signaling molecule cAMP (PubMed:12609998, PubMed:15659711, PubMed:24616449, PubMed:25040695, PubMed:24567411). May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels (PubMed:15659711, PubMed:17591988). Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization (By similarity). Involved in ciliary beat regulation (PubMed:17591988).

亚细胞位置:

Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasm Cytoskeleton Cytoplasm Perinuclear region Nucleus Cell projection Cilium Cytoplasm Mitochondrion Distributed to subcellular compartments containing cAMP targets. Found as a plasma membrane-associated protein, protein concentrated in the perinuclear region and protein colocalized with actin or tubulin.

数据库链接

UniGene:

Hs.320892

SMR:

Q96PN6

STRING:

9606.ENSP00000356825

KEGG:

hsa:55811

MIM:

143870

Pfam:

PF00211

Uniprot:

Q96PN6

相关产品

Mouse Adcy10 ELISA Kit

Rat Adcy10 ELISA Kit

Mouse Adcy10 CLIA Kit

Rat Adcy10 CLIA Kit

Mouse Adcy10 Protein

序列长度:

1610

序列:

仅供参考，详细请咨询（services@eiaab.com）

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MRANTVDNHF |

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"Soluble adenylyl cyclase is localized to cilia and contributes to ciliary beat frequency regulation via production of cAMP."

(PMID: 17591988)

[2].

"Kinetic properties of "soluble" adenylyl cyclase. Synergism between calcium and bicarbonate."

(PMID: 12609998)

[3].

"Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate."

(PMID: 24567411)

[4].

"Structural analysis of human soluble adenylyl cyclase and crystal structures of its nucleotide complexes-implications for cyclase catalysis and evolution."

(PMID: 25040695)

[5].

"Type 10 soluble adenylyl cyclase is overexpressed in prostate carcinoma and controls proliferation of prostate cancer cells."

(PMID: 23255611)

[6].

"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

(PMID: 20379614)

[7].

"Soluble adenylyl cyclase defines a nuclear cAMP microdomain in keratinocyte hyperproliferative skin diseases."

(PMID: 20130594)

[8].

"Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation."

(PMID: 19064610)

[9].

"Association of adenylate cyclase 10 (ADCY10) polymorphisms and bone mineral density in healthy adults."

(PMID: 19093065)

[10].

"Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study."

(PMID: 19536175)

[1].

人腺苷酸环化酶10(ADCY10)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人腺苷酸环化酶10(ADCY10)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人腺苷酸环化酶10(ADCY10)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人腺苷酸环化酶10(ADCY10)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人腺苷酸环化酶10(ADCY10)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人腺苷酸环化酶10(ADCY10)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人腺苷酸环化酶10(ADCY10)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人腺苷酸环化酶10(ADCY10)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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