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MSRB2 (基因名), Methionine-R-sulfoxide reductase B2, mitochondrial (蛋白名), MSRB2_HUMAN.
产品名称:

Human MSRB2/ Methionine-R-sulfoxide reductase B2, mitochondrial Recombinant Protein
线粒体蛋氨酸R亚砚还原酶B2

货号:

R14935h

商标:
EIAab®
监管等级:
别名:

CGI-131, MsrB2, CBS-1, MSRB

序列号:
Q9Y3D2
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cell Biology
Human MSRB2 Protein
规格 & 价格: cart
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Human MSRB2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 10p12.2 by HGNC 10p12.2 by Entrez Gene 10p12.2 by Ensembl
MSRB2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance.


亚细胞位置:
Mitochondrion


该产品尚未在任何出版物中被引用。

[1].
"Identification, expression and chromosome localization of a human gene encoding a novel protein with similarity to the pilB family of transcriptional factors (pilin) and to bacterial peptide methionine sulfoxide reductases."

[2].
"Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage."

[3].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."

[4].
"Differential expression of the antioxidant repair enzyme methionine sulfoxide reductase (MSRA and MSRB) in human skin."

[5].
"Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey."

[6].
"A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition."

[7].
"A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease."

[8].
"Functioning methionine sulfoxide reductases A and B are present in human epidermal melanocytes in the cytosol and in the nucleus."

[9].
"Methionine sulfoxide reduction in mammals: characterization of methionine-R-sulfoxide reductases."

[10].
"The peptide methionine sulfoxide reductases, MsrA and MsrB (hCBS-1), are downregulated during replicative senescence of human WI-38 fibroblasts."
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