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Msl2 (基因名), E3 ubiquitin-protein ligase MSL2 (蛋白名), MSL2_MOUSE.
产品名称:

Mouse Msl2/ E3 ubiquitin-protein ligase MSL2 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

E3 ubiquitin-protein transferase MSL2, Male-specific lethal 2-like 1, Male-specific lethal-2 homolog, Male-specific lethal-2 homolog 1, RING finger protein 184, MSL2-like 1, MSL-2, Kiaa1585, Msl2l1, Rnf184

序列号:
Q69ZF8
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Msl2 Protein
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Mouse Msl2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Component of a multisubunit histone acetyltransferase complex (MSL) at least composed of the KAT8/MOF/MYST1, MSL1/hampin, MSL2 and MSL3. Forms a MSL heterotetrameric core with MSL1.


功能:
Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure (By similarity). Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histone H3 methylation at 'Lys-5' (H3K4me) and 'Lys-80' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1 (By similarity).


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。
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