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MC1R (基因名), Melanocyte-stimulating hormone receptor (蛋白名), MSHR_HUMAN.
产品名称:

Human MC1R/ Melanocyte-stimulating hormone receptor Recombinant Protein
促黑激素受体

货号:

R9983h

商标:
EIAab®
监管等级:
别名:

Melanocortin receptor 1, MC1-R, MSH-R, MSHR

序列号:
Q01726
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human MC1R Protein
规格 & 价格: cart
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Human MC1R Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 16q24.3 by HGNC 16q24.3 by Entrez Gene 16q24.3 by Ensembl
MC1R Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with MGRN1, but does not undergo MGRN1-mediated ubiquitination; this interaction competes with GNAS-binding and thus inhibits agonist-induced cAMP production.


功能:
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.


亚细胞位置:
Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"MC1R: three novel variants identified in a malignant melanoma association study in the Spanish population."

[2].
"MC1R variants increase melanoma risk in families with CDKN2A mutations: a meta-analysis."

[3].
"Melanocortin 1 receptor (MC1R), pigmentary characteristics and sun exposure: findings from a case-control study of diffuse large B-cell and follicular lymphoma."

[4].
"MC1R variation and melanoma risk in the Swedish population in relation to clinical and pathological parameters."

[5].
"Germline variation of the melanocortin-1 receptor does not explain shared risk for melanoma and thyroid cancer."

[6].
"The contribution of melanocortin 1 receptor gene polymorphisms and the agouti signalling protein gene 8818A>G polymorphism to cutaneous melanoma and basal cell carcinoma in a Polish population."

[7].
"Identification and functional analysis of novel variants of the human melanocortin 1 receptor found in melanoma patients."

[8].
"Melanocortin receptor 1 variants and melanoma risk: a study of 2 European populations."

[9].
"MC1R gene polymorphism affects skin color and phenotypic features related to sun sensitivity in a population of French adult women."

[10].
"Lack of somatic alterations of MC1R in primary melanoma."
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