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MS4A3 (基因名), Membrane-spanning 4-domains subfamily A member 3 (蛋白名), MS4A3_HUMAN.
产品名称:

Human MS4A3/ Membrane-spanning 4-domains subfamily A member 3 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

CD20 antigen-like protein, Hematopoietic-specific transmembrane protein 4, HTm4, CD20L, HTM4

序列号:
Q96HJ5
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MS4A3 Protein
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Human MS4A3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 11q12.1 by HGNC 11q12.1 by Entrez Gene 11q12.1 by Ensembl
MS4A3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with CDKN3. Interacts with CDKN3-CDK2 complexes through its binding to CDKN3; this interaction facilitates dissociation of cyclin A from CDKN3-CDK2 complexes.


功能:
Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin-dependent kinase 2 (CDK2) through its direct binding to cyclin-dependent kinase inhibitor 3 (CDKN3/KAP).


亚细胞位置:
Endomembrane system Multi-pass membrane protein Cytoplasm Perinuclear region Located in the perinuclear area.


该产品尚未在任何出版物中被引用。

[1].
"Cloning of the cDNA for a hematopoietic cell-specific protein related to CD20 and the beta subunit of the high-affinity IgE receptor: evidence for a family of proteins with four membrane-spanning regions."

[2].
"Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP).Cdk2.cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2."

[3].
"Human HTm4 is a hematopoietic cell cycle regulator."

[4].
"Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men."

[5].
"An approach based on a genome-wide association study reveals candidate loci for narcolepsy."

[6].
"Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study."

[7].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[8].
"Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse."

[9].
"Structural organization of the human MS4A gene cluster on Chromosome 11q12."

[10].
"Identification of MS4A3 as a reliable marker for early myeloid differentiation in human hematopoiesis."
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